Marcó J, Tosar A, González-Barón S, Jiménez-Vargas J
Rev Esp Fisiol. 1978 Mar;34(1):81-6.
The appearance of reflex ovulation in rats under the influence of the copulation, has been studied. Evaluation of insemination, fecundation, number of embryos, ovarian cycle and ovulation in several groups of rats treated with doses of p-CPA (300 mg/Kg, i.p.), have been made. The application of p-CPA 48 hours before the estrus phase, inhibits the ovulation. This increases significantly through copulation. Reproduction is totally inhibited by p-CPA in animals under copulation conditions during 24 hours of the estrus phase. The inhibition is desappears if placed under copulation conditions during a full cycle. Inseminated rats had a 33% decrease in number of embryos with respect to the control group. The application op-CPA 24 hours before the estrus phase does not produce any inhibition effect. The decrease observed in the number of embryos is non-significant. When p-CPA is applied, instead, 48 hours before the estrus phase, there is total inhibition of the reproductive conduct.
研究了交配影响下大鼠反射性排卵的出现情况。对几组用对氯苯丙氨酸（p-CPA，300 mg/Kg，腹腔注射）处理的大鼠的授精、受精、胚胎数量、卵巢周期和排卵进行了评估。在发情期前48小时应用p-CPA可抑制排卵。通过交配，排卵显著增加。在发情期24小时的交配条件下，p-CPA完全抑制动物的繁殖。如果在整个周期内处于交配条件下，抑制作用消失。与对照组相比，授精大鼠的胚胎数量减少了33%。在发情期前24小时应用p-CPA不会产生任何抑制作用。观察到的胚胎数量减少不显著。相反，在发情期前48小时应用p-CPA时，生殖行为会完全受到抑制。
