Sawada Y, Sone K
Department of Plastic and Reconstructive Surgery, Hirosaki University School of Medicine, Japan.
Br J Plast Surg. 1992 Nov-Dec;45(8):599-603. doi: 10.1016/0007-1226(92)90027-u.
In 31 patients with hypertrophic scars or keloids, a side by side test was carried out to check the efficacy of an occlusive dressing technique using cream which did not contain silicone oil, versus a simple application of vaseline, used as a control. In all cases, the cream treated areas of scar and keloid demonstrated a remarkable improvement over that of the vaseline treated area. These findings strongly suggest that the mechanisms of hydration and occlusion are the main basis of the therapeutic action of this method in treating hypertrophic scars and keloids.
在31例增生性瘢痕或瘢痕疙瘩患者中,进行了一项对比试验,以检验使用不含硅油的乳膏的封闭敷料技术与单纯涂抹凡士林(用作对照)的疗效。在所有病例中,乳膏治疗的瘢痕和瘢痕疙瘩区域相较于凡士林治疗区域均有显著改善。这些发现有力地表明,水合作用和封闭作用机制是该方法治疗增生性瘢痕和瘢痕疙瘩的主要治疗作用基础。