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[超高频加热和热疗作用下微生物活力改变机制的比较分析]

[Comparative analysis of mechanisms of the modification of microorganism viability under the effect of UHF heating and hyperthermia].

作者信息

Kuchma T N, Alipov E D, Samoĭlenko I I, Lystsov V N

出版信息

Radiobiologiia. 1992 Nov-Dec;32(6):881-6.

PMID:1494658
Abstract

In experiments with models of isogenic Escherichia coli strains, a comparative study was made of the effect of SHF of electromagnetic field and hyperthermia. The survival rate of bacteria was determined and, simultaneously, injuries to genetic supramolecular structures were registered through measuring the anomalous time dependence of cell lysate viscosity. The combined effects of the mixture of these factors with H2O2 microconcentrations were studied. The differences observed in their realization were attributed to the different mechanisms of action of these factors on the repair enzyme systems of the studied cells. It has been found that the effect of microwaves on microorganisms causes much severer damages to DNA that hyperthermia does.

摘要

在同基因大肠杆菌菌株模型实验中,对电磁场的超高频(SHF)和热疗的效果进行了比较研究。测定了细菌的存活率,同时通过测量细胞裂解液粘度的异常时间依赖性来记录对遗传超分子结构的损伤。研究了这些因素与微量过氧化氢混合物的联合作用。观察到它们在作用过程中的差异归因于这些因素对所研究细胞修复酶系统的不同作用机制。已经发现,微波对微生物的作用比对热疗对DNA造成的损伤要严重得多。

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