Magnano G M, Piaggio G, Degl'Innocenti M L, Cariati M, Tomà P
Servizio di Radiologia, Istituto G. Gaslini, Genova.
Radiol Med. 1992 Dec;84(6):774-9.
Renal artery stenosis (RAS) in renal transplanted pediatric patients is a long-term complication. The clinical suspicion must be considered when patients exhibit signs of impaired renal function or refractory hypertension, not associated with other complications of renal transplantation -i.e., acute or chronic rejection, glomerulonephritis, cyclosporine toxicity. The intermediate step between clinical suspicion and angiography is represented by Doppler US. The authors report their experience with Doppler US in the screening of RAS in a pediatric series of transplanted patients. The incidence of RAS in our series (54 transplanted kidneys, 46 of them included in the study) was 4.3%. A severe stenosis was demonstrated by both Doppler US and angiography in 2 patients, with 100% Doppler sensitivity. In both stenoses, Doppler US showed high systolic peaks (blood flow velocity > or = 2.5 m/s) and post-stenotic turbulence. Thanks to its high sensitivity, Doppler US is considered to be very useful in the screening of vascular complications in renal transplanted children.
肾移植儿科患者的肾动脉狭窄(RAS)是一种长期并发症。当患者出现肾功能受损或难治性高血压的症状,且与肾移植的其他并发症无关时,即急性或慢性排斥反应、肾小球肾炎、环孢素毒性,必须考虑临床怀疑。临床怀疑与血管造影之间的中间步骤由多普勒超声代表。作者报告了他们在一组儿科肾移植患者中使用多普勒超声筛查RAS的经验。我们系列中的RAS发生率(54个移植肾,其中46个纳入研究)为4.3%。2例患者经多普勒超声和血管造影均显示严重狭窄,多普勒敏感性为100%。在这两种狭窄中,多普勒超声均显示收缩期峰值较高(血流速度≥2.5 m/s)和狭窄后湍流。由于其高敏感性,多普勒超声被认为在筛查肾移植儿童的血管并发症方面非常有用。