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[Disability in rheumatoid arthritis: the predictive value of age and depression].

作者信息

Salaffi F, Ferraccioli G F, Carotti M, Blasetti P, Cervini C

机构信息

Istituto Policattedra di Patologia, Università, Ancona.

出版信息

Recenti Prog Med. 1992 Dec;83(12):675-9.

PMID:1494705
Abstract

Fifty rheumatoid patients were given the Health Assessment Questionnaire (HAQ) and the Arthritis Impact Measurement Scales (AIMS) in order to determine the contribution of clinical and demographic variables to the overall disability. Among the clinical variables, pain intensity and depression were carefully assessed along with the classic morning stiffness and the joint count and tenderness/Ritchie's index. Two main findings arose: age contributed on its own to the overall disability, while disease duration had no significant effects; joint count and tenderness (Ritchie's index) correlated in a highly significant manner with depression as derived from the AIMS subscale and the Zung Depression Inventory (ZDI). ZDI items were separated into a "somatic factor" and a "dysphoric factor", showing a clear-cut influence of the somatic factor on the disability score. Our results suggest that age of the patient, pain intensity and a depressive mood related to physical impairment are chief predictive factor of the overall disability in rheumatoid arthritis.

摘要

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Soluble interleukin-2 receptor in sera and synovial fluids of rheumatoid patients: correlations with disease activity.
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