Awada A, al Rajeh S, Bademosi O, Ismail H, al Freihi H, Larbi E, Ibrahim A W
Service de Neurologie, King Faisal University, Dammam, Arabie Saoudite.
Rev Neurol (Paris). 1992;148(8-9):550-4.
We report our experience of stroke in 136 young adults aged from 18 to 45 years seen in the Eastern Province of Saudi Arabia over a 10-year period. They constituted 25% of all our stroke cases. Thirty-eight percent were Saudi nationals and 62% expatriates. Males largely outnumbered females. The frequency of cerebral infarction (54%) was not very different from that of intracranial hemorrhage (45%). Atherosclerosis and embolism of cardiac origin were the major causes of infarction. The main causes of intracranial bleeding were arterial aneurysms, arteriovenous malformations and hypertension. However, the causes of 29% of ischemic strokes and 44% of hemorrhagic ones remained undetermined. Interethnic comparison of the causes showed that hemorrhages were significantly more frequent in Far East immigrants. Sixty five percent of cerebral infarctions in Asiatic patients remained of undetermined origin. The local variant of sickle cell gene did not seem to play a major role in the pathogenesis of stroke in the Saudi young adult. These data are commented and compared with similar reported data. The influence of the demographic structures of the Saudi population and immigrants communities is analyzed.
我们报告了在沙特阿拉伯东部省份10年间诊治的136例年龄在18至45岁的年轻成年人中风患者的经验。他们占我们所有中风病例的25%。其中38%是沙特公民,62%是外籍人士。男性人数大大超过女性。脑梗死的发生率(54%)与颅内出血的发生率(45%)相差不大。动脉粥样硬化和心源性栓塞是梗死的主要原因。颅内出血的主要原因是动脉瘤、动静脉畸形和高血压。然而,29%的缺血性中风和44%的出血性中风的病因仍未明确。病因的种族间比较显示,远东移民中出血的发生率明显更高。亚洲患者中65%的脑梗死病因不明。在沙特年轻成年人中,镰状细胞基因的本地变体似乎在中风发病机制中不起主要作用。我们对这些数据进行了评论,并与已报道的类似数据进行了比较。分析了沙特人口和移民社区人口结构的影响。