Ing M R
Department of Surgery, University of Hawaii, John A. Burns School of Medicine, Honolulu.
Trans Am Ophthalmol Soc. 1992;90:361-7; discussion 367-71.
This is the first report of a group of patients with congenital esotropia examined for motor and sensory evidence of binocularity a minimum of 3 years after alignment by botulinum. Evidence for binocularity was clearly present in approximately one half of the patients. Lag time to satisfactory alignment was at least 1 month (average, 5 months) following the initial botulinum injection. The results must be considered preliminary. However, when these results are compared with those of patients with congenital esotropia aligned by incisional surgery by age 2 years and examined with the same testing devices by this same investigator, botulinum alignment appears to be less effective than surgical alignment in establishing evidence for binocularity (P < 0.005).
这是一组先天性内斜视患者的首次报告,这些患者在接受肉毒杆菌毒素使双眼矫正对齐至少3年后,接受了双眼运动和感觉方面的检查。约半数患者明显存在双眼视证据。初次注射肉毒杆菌毒素后,达到满意对齐的延迟时间至少为1个月(平均5个月)。这些结果必须视为初步结果。然而,当将这些结果与2岁时接受切开手术矫正对齐、并由同一位研究者使用相同检测设备进行检查的先天性内斜视患者的结果进行比较时,肉毒杆菌毒素矫正对齐在确立双眼视证据方面似乎不如手术矫正对齐有效(P < 0.005)。