重症肌无力中淋巴细胞与胸腺细胞之间的自身反应性。

Autoreactivity between lymphocytes and thymus cells in myasthenia gravis.

作者信息

Opelz G, Keesey J, Glovsky M M, Gale R P

出版信息

Arch Neurol. 1978 Jul;35(7):413-5. doi: 10.1001/archneur.1978.00500310015003.

DOI:10.1001/archneur.1978.00500310015003

Abstract

Thymus cell preparations from four of five myasthenia gravis patients with thymic hyperplasia and from one additional patient with thymic involution stimulated autologous peripheral blood lymphocytes. No autostimulation was observed in two patients with thymoma. Autostimulation as associated with an increase in the fraction of B lymphocytes in the thymus.

摘要

5例重症肌无力伴胸腺增生患者中的4例以及另外1例胸腺退化患者的胸腺细胞制剂刺激了自身外周血淋巴细胞。2例胸腺瘤患者未观察到自身刺激现象。自身刺激与胸腺中B淋巴细胞比例的增加有关。