免疫性疾病及HLA与重症肌无力的关联
Immune disease and HLA associations with myasthenia gravis.
作者信息
Behan P O
出版信息
J Neurol Neurosurg Psychiatry. 1980 Jul;43(7):611-21. doi: 10.1136/jnnp.43.7.611.
Abstract
In the late 1950's laboratory and clinical evidence suggested that myasthenia gravis was an autoimmune disorder. Since then a voluminous literature has developed documenting the many immunological abnormalities that occur in this condition. Recent findings point to a central disorder of immunoregulation. It is postulated that the disease occurs as a result of host genetic and environmental influences-the latter being, as yet unidentified and possibly a virus.
摘要
20世纪50年代后期，实验室和临床证据表明重症肌无力是一种自身免疫性疾病。从那时起，大量文献涌现，记录了这种疾病中出现的许多免疫异常情况。最近的研究结果指向免疫调节的核心紊乱。据推测，该病是宿主遗传和环境影响的结果——后者尚未明确，可能是一种病毒。
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Immune disease and HLA associations with myasthenia gravis.免疫性疾病及HLA与重症肌无力的关联
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