Lin J Y, Angel C, Sickel J Z
Department of Obstetrics and Gynecology, University of Rochester School of Medicine, New York.
Obstet Gynecol. 1992 Sep;80(3 Pt 2):563-6.
Elevation of serum CA 125 levels is associated with malignant serous ovarian carcinomas and has been described in one patient with Meigs syndrome. We present two additional cases of Meigs syndrome with significant elevations in serum CA 125 and report the results of immunohistochemical staining for CA 125. CA 125 expression was localized to the omentum and peritoneal surfaces rather than the fibroma. We suggest that expression of CA 125 and accumulation of ascites in these two patients may have resulted from some common peritoneal process.
血清CA 125水平升高与恶性浆液性卵巢癌相关,且已有1例梅格斯综合征患者出现该情况的报道。我们现报告另外2例血清CA 125显著升高的梅格斯综合征病例,并汇报CA 125免疫组化染色结果。CA 125表达定位于大网膜和腹膜表面,而非纤维瘤。我们认为这2例患者CA 125的表达及腹水的积聚可能源于某种共同的腹膜病变过程。