Timmerman D, Moerman P, Vergote I
Department of Obstetrics and Gynecology, University Hospitals Leuven, U.Z. Gasthuisberg, Belgium.
Gynecol Oncol. 1995 Dec;59(3):405-8. doi: 10.1006/gyno.1995.9952.
Two cases of Meigs' syndrome in association with elevated serum CA 125 levels are reported. The significance of Meigs' syndrome lies in the fact that neither ascites nor pleural effusion is necessarily an ominous sign in women with a pelvic tumor. Although there is a strong correlation between ovarian malignancy and elevated serum CA 125 levels, several benign conditions have been found to cause a rise in CA 125 levels. It is important to remember that a pelvic neoplasm in a woman presenting with hydrothorax, ascites, and elevated CA 125 levels might be benign and that this condition can rapidly be resolved with surgical removal. Neither ultrasound examination nor computed tomography can reliably offer a preoperative diagnosis.
报告了2例伴有血清CA 125水平升高的梅格斯综合征病例。梅格斯综合征的意义在于，对于患有盆腔肿瘤的女性，腹水和胸腔积液不一定是不祥之兆。虽然卵巢恶性肿瘤与血清CA 125水平升高之间存在密切关联，但已发现几种良性疾病可导致CA 125水平升高。重要的是要记住，出现胸腔积液、腹水和CA 125水平升高的女性盆腔肿瘤可能是良性的，且通过手术切除这种情况可迅速得到解决。超声检查和计算机断层扫描均不能可靠地提供术前诊断。
