[40至59岁男性的酒精消费及其与心血管疾病死亡率的关联（来自21.5年前瞻性研究的数据）]
[Alcohol consumption and its connection with mortality from cardiovascular diseases in 40-59 years old men (data from 21.5 year prospective study)].
作者信息
Aleksandri A L, Konstantinov V V, Deev A D, Kapustina A V, Shestov D B
出版信息
Ter Arkh. 2003;75(12):8-12.
AIM
To study contribution of alcohol consumption (AC) to mortality of coronary heart disease (CHD), cerebral stroke (CS), cardiovascular diseases (CVD), overall mortality (OM) in a random population of working males.
MATERIAL AND METHODS
The results are available of a 21.5 year cohort study of mortality in a random population of 7,815 male citizens of Moscow and St-Petersburg aged 40-59 years.
RESULTS
The attributive risk of AC for mortality of CHD, CS, CVD and OM was 16.6, 14.8, 7.7 and 11.9%, respectively. The lowest relative risk to die of CHD, CVD and OM among the cohort studied was observed in males taking alcohol 168.0 ml per week maximum.
CONCLUSION
It is necessary to approach differentially to assessment of AC effects on development of many diseases and further investigations are needed to reveal fine mechanisms of action of different alcohol drinks on human organism.
目的
研究饮酒对随机选取的在职男性人群冠心病（CHD）、脑卒 中（CS）、心血管疾病（CVD）死亡率及总死亡率（OM）的影响。
材料与方法
对莫斯科和圣彼得堡7815名年龄在40至59岁的男性公民进行了为期21.5年的随机人群死亡率队列研究，现已有相关结果。
结果
饮酒对冠心病、脑卒中、心血管疾病和总死亡率的归因风险分别为16.6%、14.8%、7.7%和11.9%。在该队列研究中，每周饮酒量最大为168.0毫升的男性死于冠心病、心血管疾病和总死亡率的相对风险最低。
结论
有必要区别对待饮酒对多种疾病发展的影响评估，还需要进一步研究以揭示不同酒精饮料对人体作用的精细机制。
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