Wilson I G
Northern Ireland Public Health Laboratory, Bacteriology Department, Belfast City Hospital, Lisburn Road, Belfast BT9 7AD, UK.
Epidemiol Infect. 2003 Dec;131(3):1181-6. doi: 10.1017/s0950268803001298.
Campylobacter isolates from raw retail chickens (n = 434) sampled between 1998 and 2000 were tested for resistance to 12 antibiotics. Among 208 campylobacters tested, more than 90% of isolates were susceptible to 4 out of 9 antibiotics (nalidixic acid, erythromycin, chloramphenicol and gentamicin). Most campylobacters were resistant to 3 antibiotics and multiple resistance was found in 4%. Ciprofloxacin resistance was 11%. Campylobacter contamination (28%) in imported chickens (n = 150) was almost half that found in local whole chickens (50%), but the resistance of imported isolates (n = 42) was similar to that of local campylobacters. Resistance in isolates from imported chicken breasts was generally more common, but to only 4 antibiotics. Resistance patterns of chicken isolates were compared to human clinical isolates (n = 494), and a greater similarity was found between the clinical and local isolates than with imported campylobacters. Lower chloramphenicol resistance was found in clinical Campylobacter isolates than in those from chicken sources.
对1998年至2000年间采集的434份零售生鲜鸡肉中的弯曲杆菌分离株进行了12种抗生素的耐药性检测。在检测的208株弯曲杆菌中，超过90%的分离株对9种抗生素中的4种（萘啶酸、红霉素、氯霉素和庆大霉素）敏感。大多数弯曲杆菌对3种抗生素耐药，4%的菌株存在多重耐药。环丙沙星耐药率为11%。进口鸡肉（n = 150）中的弯曲杆菌污染率（28%）几乎是本地整鸡（50%）的一半，但进口分离株（n = 42）的耐药性与本地弯曲杆菌相似。进口鸡胸肉分离株的耐药情况通常更常见，但仅针对4种抗生素。将鸡肉分离株的耐药模式与人类临床分离株（n = 494）进行比较，发现临床分离株与本地分离株之间的相似性高于与进口弯曲杆菌的相似性。临床弯曲杆菌分离株中的氯霉素耐药性低于鸡肉来源的分离株。
