Coget J M, Millien J P
Phlebologie. 1992 Jan-Mar;45(1):9-16.
Since the report of the 1st International Conference of Phlebology at Chambéry, devoted to venous pain, the subject has scarcely attracted attention apart from the meeting of the Benelux Society of Phlebology devoted to "pain in the legs". Pain due to superficial venous insufficiency has scarcely changed in nature for 30 years and remains one of the major presenting symptoms in phlebology. Acute or chronic, punctate or diffuse, modifications in this functional symptomatology have been accentuated, or have varied in their aspects under the influence of certain fashions or certain habits of modern life, i.e.: sedentary behaviour, underfloor heating, the use of oral contraceptives or of menopausal hormone replacement therapy. However, the distribution of the various aspects of venous pain remains in the same proportions as those described by the authors cited previously. While the etiological diagnosis must essentially eliminate all other causes: arterial, neurological, muscular, articular, it is essential not to neglect deep venous insufficiency of the gemellar veins, often responsible for a wide range of symptomatology and still all too often neglected. The pathogenesis of this pain not only involves the concept of pain receptors but also the appearance of algogenic metabolites at the site of the microcirculatory unit, to which endothelial cells are particularly sensitive during stasis. In fact, pain is the expression of disorders concerning local exchanges, whether thermal, pressure, metabolic or hemorheological. It is the alarm bell of venous insufficiency and merits the attention of the phebologist who must thus undertake active treatment before problems become irreversible.
自尚贝里第一届国际静脉学会议报告专注于静脉疼痛以来,除了比荷卢静脉学协会关于“腿部疼痛”的会议外,该主题几乎未受到关注。因浅静脉功能不全导致的疼痛在本质上30年来几乎没有变化,仍然是静脉学主要的就诊症状之一。急性或慢性、点状或弥漫性,这种功能性症状的改变在某些时尚潮流或现代生活习惯的影响下有所加剧,或在表现形式上有所变化,即:久坐行为、地板供暖、口服避孕药或更年期激素替代疗法的使用。然而,静脉疼痛各方面的分布比例仍与先前引用的作者所描述的相同。虽然病因诊断必须首先排除所有其他原因:动脉、神经、肌肉、关节方面的原因,但绝不能忽视腘静脉的深静脉功能不全,它常常导致多种症状,却仍然常常被忽视。这种疼痛的发病机制不仅涉及痛觉感受器的概念,还涉及微循环单位部位致痛代谢产物的出现,在血流淤滞时内皮细胞对此特别敏感。事实上,疼痛是局部交换紊乱的表现,无论是热交换、压力交换、代谢交换还是血液流变学交换。它是静脉功能不全的警钟,值得静脉学专家关注,因此专家必须在问题变得不可逆转之前进行积极治疗。