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检测两个计量性状基因间连锁的数值方法。

Numerical method for detection of linkage between genes for two metrical traits.

作者信息

Kaczmarek Zygmunt, Surma Maria, Adamski Tadeusz, Czajka Stanisław

机构信息

Institute of Plant Genetics, Polish Academy of Sciences, Poznán, Poland.

出版信息

J Appl Genet. 2004;45(1):27-35.

Abstract

A homozygous population derived from hybrids between two homozygous parents may be used for genetic analysis of metrical traits. The paper describes the use of doubled haploids (DH) and single seed descent (SSD) lines for detection of linkage between genes conditioning two quantitative traits. A computational algorithm is presented, which facilitates matching various variants of relations between variances, covariances and means of DH and SSD populations so as to make it possible to conclude on the presence/absence of linkage. The suggested methodology is illustrated with an example concerning three quantitative traits of barley: length of the third internode, stem wall thickness, and 1000-grain weight.

摘要

由两个纯合亲本杂交产生的纯合群体可用于计量性状的遗传分析。本文描述了利用双单倍体(DH)和单粒传(SSD)株系检测控制两个数量性状的基因之间的连锁关系。提出了一种计算算法,该算法有助于匹配DH和SSD群体的方差、协方差和均值之间关系的各种变体,从而能够推断连锁关系的存在与否。通过一个关于大麦三个数量性状的例子说明了所建议的方法:第三节间长度、茎壁厚度和千粒重。

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