0.5%布比卡因肋间神经阻滞对肋骨骨折患者呼气峰值流速和动脉血氧饱和度的影响
Effect of intercostal nerve block with 0.5% bupivacaine on peak expiratory flow rate and arterial oxygen saturation in rib fractures.
作者信息
Osinowo Olu A, Zahrani Mohammed, Softah Abdullateef
机构信息
Department of Surgery, Assir Central Hospital and College of Medicine, King Kholid University, Abha, Saudi, Arabia.
出版信息
J Trauma. 2004 Feb;56(2):345-7. doi: 10.1097/01.TA.0000046257.70194.2D.
BACKGROUND
This prospective study was undertaken to evaluate the efficiency of intercostal nerve block (ICNB) with 0.5% bupivacaine (Marcaine) for pain relief in patients with rib fractures and to correlate the degree of pain relief with changes in the peak expiratory flow rate (PEFR) and oxygen saturation (Sao2).
METHODS
Twenty-one consecutive adult patients admitted with rib fractures associated with severe pain formed the basis of the study. Chest pain was scored on a four-point scale before ICNB, 1 hour after ICNB, and 24 hours after ICNB. Sao2 was measured before and immediately after ICNB. PEFR was measured before and immediately after ICNB.
RESULTS
Pain score and PEFR before and after ICNB showed statistically significant differences (p = 0.0000, df = 20). There was a significant difference between Sao2 before and after ICNB.
CONCLUSION
Significant increases in Sao2 and PEFR occur after ICNB with 0.5% bupivacaine, which also provides sustained analgesia, leading to improvement in respiratory mechanics.
背景
本前瞻性研究旨在评估0.5%布比卡因（耐乐品）肋间神经阻滞（ICNB）对肋骨骨折患者的镇痛效果，并将疼痛缓解程度与呼气峰值流速（PEFR）和血氧饱和度（Sao2）的变化相关联。
方法
21例因肋骨骨折伴严重疼痛入院的成年连续患者构成了本研究的基础。在ICNB前、ICNB后1小时和ICNB后24小时，采用四点量表对胸痛进行评分。在ICNB前和ICNB后即刻测量Sao2。在ICNB前和ICNB后即刻测量PEFR。
结果
ICNB前后的疼痛评分和PEFR显示出统计学上的显著差异（p = 0.0000，自由度 = 20）。ICNB前后的Sao2存在显著差异。
结论
0.5%布比卡因ICNB后，Sao2和PEFR显著增加，同时还提供持续镇痛，从而改善呼吸力学。
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