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前瞻性、随机对照研究:连续胸椎硬膜外阻滞与胸椎旁神经阻滞用于单侧多发性肋骨骨折患者的疗效比较——一项初步研究

Prospective, randomized comparison of continuous thoracic epidural and thoracic paravertebral infusion in patients with unilateral multiple fractured ribs--a pilot study.

作者信息

Mohta Medha, Verma Priyanka, Saxena Ashok Kr, Sethi Ashok K, Tyagi Asha, Girotra Gautam

机构信息

Department of Anesthesiology and Critical Care, University College of Medical Sciences, Guru Teg Bahadur Hospital, Delhi, India.

出版信息

J Trauma. 2009 Apr;66(4):1096-101. doi: 10.1097/TA.0b013e318166d76d.

Abstract

BACKGROUND

Thoracic epidural analgesia (TEA), a commonly used analgesic technique in patients with multiple fractured ribs, is technically demanding and associated with certain side effects or complications. Thoracic paravertebral block (TPVB) is a simple and effective method of providing continuous pain relief in these patients. However, it has never been compared with TEA in terms of efficacy and outcome in patients with fractured ribs.

METHODS

Thirty adult patients of either sex, having three or more unilateral fractured ribs, were randomized to receive continuous bupivacaine infusion through either thoracic epidural or thoracic paravertebral catheter. Visual Analog Scale scores at rest and on coughing, respiratory rate, peak expiratory flow rate, and PaO2/FIO2 ratio were measured before and after administration of block at regular intervals. Morphine requirement for rescue analgesia, duration of bupivacaine infusion, length of intensive care unit and hospital stay, development of pulmonary complications, and complications of the two techniques were also recorded.

RESULTS

Both TEA and TPVB provided good pain relief and improved respiratory function, as evident by improvement in Visual Analog Scale scores at rest and on coughing, respiratory rate, and peak expiratory flow rate. However, no significant intergroup differences were found. Duration of bupivacaine infusion, morphine requirement, length of intensive care unit and hospital stay, and incidence of pulmonary complications were also similar in the two groups. Incidence of hypotension was more in TEA group.

CONCLUSIONS

Continuous bupivacaine infusion through TPVB is as effective as through TEA for pain management in patients with unilateral fractured ribs and the outcome after two techniques is comparable.

摘要

背景

胸段硬膜外镇痛(TEA)是多根肋骨骨折患者常用的镇痛技术,操作要求高且伴有一定的副作用或并发症。胸段椎旁阻滞(TPVB)是为这些患者提供持续疼痛缓解的一种简单有效的方法。然而,在肋骨骨折患者的疗效和预后方面,它从未与TEA进行过比较。

方法

30例成年患者,无论男女,单侧肋骨骨折3根及以上,随机分为通过胸段硬膜外或胸段椎旁导管持续输注布比卡因。在阻滞给药前后定期测量静息和咳嗽时的视觉模拟评分、呼吸频率、呼气峰值流速和PaO2/FIO2比值。还记录了用于补救镇痛的吗啡需求量、布比卡因输注持续时间、重症监护病房和住院时间、肺部并发症的发生情况以及两种技术的并发症。

结果

TEA和TPVB均能提供良好的疼痛缓解并改善呼吸功能,静息和咳嗽时的视觉模拟评分、呼吸频率和呼气峰值流速的改善即可证明。然而,未发现显著的组间差异。两组布比卡因输注持续时间、吗啡需求量、重症监护病房和住院时间以及肺部并发症发生率也相似。TEA组低血压发生率更高。

结论

对于单侧肋骨骨折患者,通过TPVB持续输注布比卡因在疼痛管理方面与通过TEA一样有效,两种技术的预后相当。

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