Zdrenghea D, Iancu A, Gligor E
Department of Cardiology, Clinical Hospital of Rehabilitation, Cluj-Napoca, Romania.
Rom J Intern Med. 1992 Jan-Mar;30(1):31-4.
The paper tested the hypothesis that supraventricular tachyarrhythmias (SVT) could represent the first clinical manifestation of the sick sinus syndrome (SSS). Absolute sinus node recovery time (SNRT) and sinoatrial conduction time (SACT) were determined through transesophageal approach in 16 patients with paroxysmal SVT, but without bradycardic episodes between crises. The values considered normal were: SNRTa less than or equal to less than or equal to 1500 ms; SNRTc less than or equal to 525 ms; SACT less than or equal to 150 ms. SNRTa, SNRTc and SACT were normal in all subjects (SNRTa: 1077 ms; SNRTc: 400 ms; SACT: 111 ms) and suggest the absence of a notable sinusal disfunction in these patients. We concluded that SVT unassociated with bradycardia do not usually represent a manifestation of SSS. Consequently the administration of sinusal depressant drugs in such patients could be permitted without restrictions.
该论文检验了室上性快速心律失常（SVT）可能是病态窦房结综合征（SSS）的首发临床表现这一假说。通过经食管途径测定了16例阵发性SVT患者的绝对窦房结恢复时间（SNRT）和窦房传导时间（SACT），这些患者在发作间期无心动过缓发作。正常数值为：SNRTa小于或等于1500毫秒；SNRTc小于或等于525毫秒；SACT小于或等于150毫秒。所有受试者的SNRTa、SNRTc和SACT均正常（SNRTa：1077毫秒；SNRTc：400毫秒；SACT：111毫秒），提示这些患者不存在明显的窦房结功能障碍。我们得出结论，不伴有心动过缓的SVT通常不代表SSS的表现。因此，在此类患者中可无限制地使用窦房结抑制药物。
