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糖尿病与运动。

Diabetes and exercise.

作者信息

Santeusanio F, Di Loreto C, Lucidi P, Murdolo G, De Cicco A, Parlanti N, Piccioni F, De Feo P

机构信息

Department of Internal Medicine, Section Internal Medicine, Endocrine and Metabolic Sciences, University of Perugia, Perugia, Italy.

出版信息

J Endocrinol Invest. 2003 Sep;26(9):937-40. doi: 10.1007/BF03345247.

Abstract

Physical activity has acute and chronic effects on glucose, lipid and protein metabolism. Long-term effects of regular exercise are particularly advantageous for Type 2 diabetic patients. Regular aerobic exercise reduces visceral fat mass and body weight without decreasing lean body mass, ameliorates insulin sensitivity, glucose and BP control, lipid profile and reduces the cardiovascular risk. For these reasons, regular aerobic physical activity must be considered as an essential component of the cure of Type 2 diabetes mellitus. In this regard, individual behavioral strategies have been documented to be effective in motivating sedentary Type 2 diabetic subjects to the adoption and the maintenance of regular physical activity. In Type 1 diabetic subjects, the lack of the physiological inhibition of insulin secretion during exercise results in a potential risk of hypoglycemia. On the other hand, exercise-induced activation of counter-regulatory hormones might trigger an acute metabolic derangement in severe insulin-deficient subjects. Thus, diabetic patients, before starting exercise sessions, must be carefully educated about the consequences of physical activity on their blood glucose and the appropriate modifications of diet and insulin therapy.

摘要

体育活动对糖、脂质和蛋白质代谢有急性和慢性影响。规律运动的长期效果对2型糖尿病患者尤为有益。规律的有氧运动可减少内脏脂肪量和体重,而不减少瘦体重,改善胰岛素敏感性、血糖和血压控制、血脂谱,并降低心血管风险。基于这些原因,规律的有氧体育活动必须被视为2型糖尿病治疗的重要组成部分。在这方面,有文献记载个体行为策略在激励久坐不动的2型糖尿病患者采用并维持规律体育活动方面是有效的。在1型糖尿病患者中,运动期间胰岛素分泌缺乏生理抑制会导致低血糖的潜在风险。另一方面,运动诱导的反调节激素激活可能在严重胰岛素缺乏的患者中引发急性代谢紊乱。因此,糖尿病患者在开始运动前,必须就体育活动对其血糖的影响以及饮食和胰岛素治疗的适当调整接受仔细的教育。

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