Ben-David J, Luntz M, Magamsa I, Fradis M, Sabo E, Podoshin L
Department of Otolaryngology-Head and Neck Surgery, Bnai-Zion Medical Center, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Int Tinnitus J. 2001;7(1):62-4.
Idiopathic sudden sensorineural hearing loss remains a controversial problem with respect to etiology and the factors that might predict a favorable prognosis. This study evaluated the possible prognostic factors of recovery in 67 patients with idiopathic sensorineural hearing loss treated with steroids (prednisone), plasma expanders (intravenous dextran), and vasodilators (papaverine). Clinical recovery was estimated by contrasting the audiometric results on admission and those at discharge 10 days later. The correlation between various potential prognostic factors and audiological improvement was calculated. Only two factors were found to be associated significantly with hearing improvement: tinnitus (p < .04) and the slope of audiogram on admission (p < .045). Tinnitus and the presence of an ascending audiogram were found to be correlated with a favorable outcome in idiopathic sensorineural hearing loss.
特发性突发性感音神经性听力损失在病因以及可能预示良好预后的因素方面仍是一个有争议的问题。本研究评估了67例接受类固醇（泼尼松）、血浆扩容剂（静脉注射右旋糖酐）和血管扩张剂（罂粟碱）治疗的特发性感音神经性听力损失患者恢复的可能预后因素。通过对比入院时和10天后出院时的听力测试结果来评估临床恢复情况。计算了各种潜在预后因素与听力改善之间的相关性。仅发现两个因素与听力改善显著相关：耳鸣（p < 0.04）和入院时听力图的斜率（p < 0.045）。耳鸣和听力图呈上升趋势与特发性感音神经性听力损失的良好预后相关。
