Navo Marisa A, Phan Julie, Vaughan Christy, Palmer J Lynn, Michaud Laura, Jones Kellie L, Bodurka Diane C, Basen-Engquist Karen, Hortobagyi Gabriel N, Kavanagh John J, Smith Judith A
College of Pharmacy, University of Houston, TX, USA.
J Clin Oncol. 2004 Feb 15;22(4):671-7. doi: 10.1200/JCO.2004.04.162.
To describe and assess the current utilization of complementary and alternative medicines (CAMs) in women with a diagnosis of either gynecologic or breast cancer and evaluate their reasons for use.
This study included 250 female patients from the Multidisciplinary Breast Center and 250 patients from the Gynecologic Oncology Center of The University of Texas M.D. Anderson Cancer Center (Houston, TX). Patients were selected by having an odd-numbered medical record number, and they were contacted before their clinic visit. The goals of the study were explained, and verbal consent was obtained. Patients who agreed to participate were asked to bring a written list and the medication bottles of all over-the-counter prescriptions and CAMs with them to clinic. In clinic, the investigator obtained a written informed consent and administered the survey. All patients and surveys were assessable.
The most frequently used herbal products and megavitamins/minerals were identified from the patient medication histories. Overall, we found the proportion of patients using CAM to be 48% (95% CI, 44% to 53%; 241 of 500 patients). CAM use was related to patients' educational status: 62% had postgraduate degrees, 50% had college degrees, 56% had some college, and 33% had a high school education or less. Also, among patients using CAMs, only 53.5% had spoken to a healthcare provider regarding CAM therapy.
The use of CAM is common among women with cancer. Studies need to be conducted to establish if there are any potential drug interactions and/or therapeutic benefit of CAM products. Moreover, there is a need to educate patients and healthcare providers on appropriate and safe use of CAM products.
描述和评估被诊断患有妇科癌症或乳腺癌的女性对补充和替代医学（CAMs）的当前使用情况，并评估她们使用的原因。
本研究纳入了得克萨斯大学MD安德森癌症中心（休斯顿，得克萨斯州）多学科乳腺中心的250名女性患者以及妇科肿瘤中心的250名患者。通过选取病历号为奇数的患者，并在其门诊就诊前与她们联系。解释了研究目的并获得了口头同意。同意参与的患者被要求携带一份书面清单以及所有非处方处方药和补充与替代医学产品的药瓶前往门诊。在门诊，研究者获得了书面知情同意并进行了调查。所有患者和调查均可评估。
从患者用药史中确定了最常用的草药产品和多种维生素/矿物质。总体而言，我们发现使用补充与替代医学的患者比例为48%（95%可信区间，44%至53%；500名患者中的241名）。补充与替代医学的使用与患者的教育程度有关：62%拥有研究生学位，50%拥有大学学位，56%上过一些大学课程，33%接受过高中及以下教育。此外，在使用补充与替代医学的患者中，只有53.5%曾就补充与替代医学疗法与医疗服务提供者交谈过。
补充与替代医学在癌症女性患者中使用普遍。需要开展研究以确定补充与替代医学产品是否存在任何潜在的药物相互作用和/或治疗益处。此外，有必要对患者和医疗服务提供者进行关于补充与替代医学产品适当和安全使用的教育。
