Markina V V, Romanov Yu A
Department of Biology, Moscow State Medical and Stomatological University, Russia.
Bull Exp Biol Med. 2003 Nov;136(5):499-502. doi: 10.1023/b:bebm.0000017104.38937.7c.
We evaluated spatiotemporal characteristics of glycogen content in cells of rat liver lobule. Glycogen content in the liver lobule and its circulatory subzones underwent diurnal fluctuations with acrophase at 5.00. Spatial changes were characterized by a dependence of gradients in the lobule on the phase of diurnal rhythmic fluctuations. Total glycogen content in the peripheral subzone of the lobule 5.2-fold surpassed that in the central subzone. Our results illustrate spatiotemporal organization of glycogen content in the liver lobule.
我们评估了大鼠肝小叶细胞中糖原含量的时空特征。肝小叶及其循环亚区中的糖原含量呈现昼夜波动，峰值相位在5:00。空间变化的特征是小叶中的梯度依赖于昼夜节律波动的相位。小叶外周亚区的总糖原含量比中央亚区高5.2倍。我们的结果阐明了肝小叶中糖原含量的时空组织。
