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[不同检测系统在人类免疫缺陷病毒抗体筛查测定中的诊断价值]

[The diagnostic value of different test systems for the screening determination of antibodies to the human immunodeficiency virus].

作者信息

Morozov V G, Sheĭbak V V, Selivanov A A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1992 Apr(4):17-9.

PMID:1496872
Abstract

Evaluation of the quality of enzyme immunoassay (EIA) systems by their sensitivity and specificity is inadequate, mainly due to the impossibility of detecting early or latent HIV infection in humans as it manifests by seroconversion only to a few HIV proteins. The additional evaluation criterion (confirmation rate) has been introduced, and an original method for the integral evaluation of the quality of assay systems intended for the diagnosis of HIV infection by EIA techniques has been proposed.

摘要

通过酶免疫测定(EIA)系统的灵敏度和特异性来评估其质量是不够的,主要原因是无法检测人类早期或潜伏性HIV感染,因为只有在血清转化为少数HIV蛋白时才会表现出来。已经引入了额外的评估标准(确认率),并提出了一种通过EIA技术对用于诊断HIV感染的检测系统质量进行综合评估的原始方法。

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