Kalenova L F, Zolotukhin V A, Kashuba E A, Kostina G I, Postnikova T F
Zh Mikrobiol Epidemiol Immunobiol. 1992 Apr(4):20-2.
Superinfection of animals having Opisthorchis invasion with Mycobacterium tuberculosis leads to destabilization of host-parasite relationships in opisthorchiasis and formation of new host-parasitocenotic interrelations whose manifestation depends on the phase of the invasive process. At the acute invasive phase of mixed pathology (2 weeks) the activity of the host's immune system increases, while the biological activity of helminths and the number of M. tuberculosis colonies decrease. And on the contrary, at the subacute phase of mixed pathology (2.5 months) the activity of the host's immune system decreases, while the reproductive activity of helminths and the isolation rate of M. tuberculosis from pulmonary tissue increases in comparison with the groups of animals with monoinvasion and monoinfection.
感染华支睾吸虫的动物再感染结核分枝杆菌会导致华支睾吸虫病中宿主与寄生虫关系的不稳定，并形成新的宿主 - 寄生虫群落间相互关系，其表现取决于侵袭过程的阶段。在混合病理的急性侵袭期（2周），宿主免疫系统的活性增加，而蠕虫的生物活性和结核分枝杆菌菌落数量减少。相反，在混合病理的亚急性期（2.5个月），宿主免疫系统的活性降低，与单一侵袭和单一感染的动物组相比，蠕虫的繁殖活性以及从肺组织中分离出结核分枝杆菌的比率增加。
