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[实验性后睾吸虫病和结核感染金黄仓鼠肝脏及免疫系统器官的病理形态学变化]

[The pathomorphological changes in the liver and immune system organs of golden hamsters with experimental opisthorchiasis and tuberculosis infections].

作者信息

Lazareva O A, Zolotukhin V A, Kalenova L F

出版信息

Med Parazitol (Mosk). 1991 Mar-Apr(2):16-8.

PMID:2067486
Abstract

It has been established that lymphoid tissue involution caused by mixed experimental tuberculosis-opisthorchiasis infection was accompanied by a considerable attenuation of fibrosis and less intensive inflammatory destructive changes and liver fibrosis, as compared to monoinvasion with opisthorchis. In mixed infection there was a decrease in immunoreactivity of animals as assessed by the number of antibody-forming spleen cells per immunization with sheep red blood cells, compared to opisthorchiasis monoinvasion and a slight increase in this parameter compared to tuberculosis monoinfection.

摘要

已经确定,与单纯华支睾吸虫感染相比,混合实验性结核-华支睾吸虫感染引起的淋巴组织退化伴随着纤维化的显著减轻以及炎症性破坏变化和肝纤维化程度的降低。与华支睾吸虫单感染相比,混合感染时,通过每次用绵羊红细胞免疫后抗体形成脾细胞的数量评估,动物的免疫反应性降低;与结核单感染相比,该参数略有增加。

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