Cohn S M, Lopez P P, Brown M, Namias N, Jackowski J, Li P, Mishkin D, Lopez J M
Department of Surgery, Divisions of Trauma and Surgical Critical Care, University of Miami School of Medicine, USA.
J Wound Care. 2004 Jan;13(1):10-2. doi: 10.12968/jowc.2004.13.1.26556.
To compare the healing rates of a hydrofibre dressing (Aquacel) and normal wet-to-dry gauze in the treatment of open surgical wounds.
Fifty patients with open surgical wounds were randomized to receive either saline-moistened gauze or Aquacel. The rate of wound healing was measured as ml/day (deep wounds) or cm2/day (superficial wounds) at each dressing change until an investigator blinded to the patient group diagnosed the wounds as having healed or the patient was withdrawn from the study.
Of the 50 patients, seven were withdrawn from the study after the first evaluation. Of the remaining 43 patients, 21 had been randomly allocated to the gauze group and 22 to the Aquacel group. For deep wounds, a mean change in the wound healing rate of 1.9 +/- 1.3 cm3/day was reported for the gauze group and 2.9 +/- 2.3 cm3/day for the Aquacel group. These results approach statistical significance (p = 0.082). For superficial wounds, the mean change in the healing rate was 1.6 +/- 1.5 cm2/day for the gauze group and 1.9 +/- 2.2 cm2/day for the Aquacel group, but this was not statistically significant.
Aquacel appears to be at least as effective as wet-to-dry gauze in the healing of open surgical wounds.
比较水凝胶敷料（爱康肤银）与普通湿-干纱布在开放性手术伤口治疗中的愈合率。
50例开放性手术伤口患者被随机分为两组，分别使用生理盐水湿润的纱布或爱康肤银。每次换药时测量伤口愈合率，以毫升/天（深部伤口）或平方厘米/天（浅表伤口）为单位，直至对患者分组不知情的研究者判定伤口已愈合或患者退出研究。
50例患者中，7例在首次评估后退出研究。其余43例患者中，21例被随机分配至纱布组，22例被分配至爱康肤银组。对于深部伤口，纱布组伤口愈合率平均变化为1.9±1.3立方厘米/天，爱康肤银组为2.9±2.3立方厘米/天。这些结果接近统计学显著性（p = 0.082）。对于浅表伤口，纱布组愈合率平均变化为1.6±1.5平方厘米/天，爱康肤银组为1.9±2.2平方厘米/天，但无统计学显著性。
在开放性手术伤口愈合方面，爱康肤银似乎至少与湿-干纱布同样有效。
