Clin Exp Rheumatol. 2003 Sep-Oct;21(5 Suppl 31):S129-32.
The Italian Society of Rheumatology in the year 2000 decided to sponsor the creation of a data base (Registry) of consecutive patients who fulfilled the diagnosis of rheumatoid arthritis (RA) according to the American College of Rheumatology (ACR) criteria. The registry is designed to collect data on the "aggressive" type of RA all over the country in order to determine the percentage of patients who satisfy the established criteria among incident cases of RA and to define the therapeutic approach according to the characteristics of the enrolled patients. Predefined criteria set up by eight recognized opinion leaders on the disease were used by all the centers to create the database. The GIARA registry (Gruppo Italiano Artrite Reumatoide Aggressiva) has now enrolled 706 patients who will be followed up for 24 months. They have been divided into two major subsets--patients with early (< 4 months' disease duration) and late (> 4 months) RA--with the aim of establishing whether differences in clinical, serological, radiographic and therapeutic (DMARDs: disease modifying antirheumatic drugs) parameters may distinguish the two subsets. The major conclusion of this preliminary analysis is that an overall tendency to undertreatment is discernable.
2000年，意大利风湿病学会决定资助建立一个数据库（登记处），收录根据美国风湿病学会（ACR）标准确诊为类风湿关节炎（RA）的连续病例。该登记处旨在收集全国范围内“侵袭性”RA患者的数据，以确定在RA新发病例中符合既定标准的患者比例，并根据登记患者的特征确定治疗方法。所有中心均采用由八位该疾病领域公认的意见领袖制定的预定义标准来创建数据库。GIARA登记处（意大利侵袭性类风湿关节炎研究组）现已收录706例患者，将对其进行为期24个月的随访。这些患者被分为两个主要亚组——疾病病程<4个月的早期RA患者和病程>4个月的晚期RA患者——目的是确定临床、血清学、影像学和治疗（改善病情抗风湿药物：DMARDs）参数的差异是否可以区分这两个亚组。这项初步分析的主要结论是，可看出总体上存在治疗不足的倾向。
