Sáenz-Santamaría Javier, Catalina-Fernandez Inmaculada
Department of Pathology, Hospital Perpetuo Socorro, Avda. Damián Téllez Lafuente s/n, 06010, Badajoz, Spain.
Acta Cytol. 2004 Jan-Feb;48(1):52-6. doi: 10.1159/000326283.
To describe the fine needle aspiration cytology findings of polymorphous low grade adenocarcinoma of the salivary gland.
The authors reviewed the cytologic findings of 5 cases of polymorphous low grade adenocarcinoma. All cases were confirmed by histologic examination.
All cases showed similar cytologic findings. The smears had high cellularity with a population of mixed epithelial and myoepithelial cells. These cells formed branching papillae, sheets and clusters. The epithelial cells were uniform, with round to ovoid nuclei; absent or inconspicuous nucleoli; and a moderate amount of dense cytoplasm. Occasionally the cells formed spherical structures containing hyaline globules. Myxoid matrix, either dispersed in the background or interspersed with the cellular elements, was also seen often.
Polymorphous low grade adenocarcinoma should be cytologically differentiated from adenoid cystic carcinoma, monomorphic adenoma and pleomorphic adenoma. Recognition of subtle cytologic features. may be useful in the differential diagnosis.
描述涎腺多形性低度恶性腺癌的细针穿刺细胞学检查结果。
作者回顾了5例多形性低度恶性腺癌的细胞学检查结果。所有病例均经组织学检查确诊。
所有病例均显示相似的细胞学检查结果。涂片细胞丰富，有混合的上皮细胞和肌上皮细胞。这些细胞形成分支乳头、片状和团块状。上皮细胞形态一致，核呈圆形至卵圆形；核仁缺如或不明显；胞质丰富且致密。偶尔细胞形成含透明小球的球形结构。黏液样基质也常见，或分散于背景中，或夹杂于细胞成分之间。
多形性低度恶性腺癌在细胞学上应与腺样囊性癌、单形性腺瘤和多形性腺瘤相鉴别。识别细微的细胞学特征可能有助于鉴别诊断。
