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伴有乳头的涎腺癌:多形性低度恶性腺癌和乳头状囊腺癌的细胞学与组织学分析

Salivary carcinomas with papillae: cytology and histology analysis of polymorphous low-grade adenocarcinoma and papillary cystadenocarcinoma.

作者信息

Klijanienko J, Vielh P

机构信息

Département de Pathologie, Institut Curie, Paris, France.

出版信息

Diagn Cytopathol. 1998 Oct;19(4):244-9. doi: 10.1002/(sici)1097-0339(199810)19:4<244::aid-dc3>3.0.co;2-a.

Abstract

We retrospectively compared fine-needle samplings (FNS) from two recently individualized low-grade papillary salivary carcinomas, polymorphous low-grade adenocarcinoma (PLGAC) and papillary cystadenocarcinoma (PCAC), to define the cytologic criteria allowing the correct diagnosis. Twelve PLGACs in 10 patients and 5 PCACs in 4 patients were investigated by FNS preoperatively. In both entities, smears contained variable proportions of malignant cells, occasionally arranged in pseudopapillary formations. In contrast to PCAC, PLGAC showed stromal fragments and hyaline globules resembling pleomorphic adenoma or adenoid cystic carcinoma. Cytologic diagnoses of malignancy were established in 10 (83.3%) PLGACs and in 4 (80%) PCACs. Two (16.7%) PLGACs were misdiagnosed as pleomorphic adenoma, and 1 (20%) PCAC as a salivary cyst.

摘要

我们回顾性比较了来自两种近期个体化的低级别乳头状唾液腺癌——多形性低级别腺癌(PLGAC)和乳头状囊腺癌(PCAC)的细针采样(FNS),以确定能够做出正确诊断的细胞学标准。术前通过FNS对10例患者的12例PLGAC和4例患者的5例PCAC进行了研究。在这两种实体肿瘤中,涂片含有不同比例的恶性细胞,偶尔呈假乳头状结构排列。与PCAC不同,PLGAC显示出类似于多形性腺瘤或腺样囊性癌的间质碎片和透明小球。10例(83.3%)PLGAC和4例(80%)PCAC做出了恶性的细胞学诊断。2例(16.7%)PLGAC被误诊为多形性腺瘤,1例(20%)PCAC被误诊为唾液囊肿。

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