Watanabe K, Ono N, Saito K, Saito A, Suzuki T
Division of Pathology, Fukushima Medical University School of Medicine Hospital, Fukushima City, Japan.
Diagn Cytopathol. 1999 Mar;20(3):167-9. doi: 10.1002/(sici)1097-0339(199903)20:3<167::aid-dc11>3.0.co;2-q.
The cytologic features derived from a fine-needle aspiration of polymorphous low-grade adenocarcinoma (PLGA) of the base of the tongue are described. The tumor cells were composed of cuboidal epithelial cells and short, spindle-shaped myoepithelial-like cells, and they formed large cell clusters. In the central portion of the clusters, myxoid materials were present, and palisading tumor cells occasionally surrounded them. Histological examination revealed solid proliferation of the epithelial cuboidal and spindle cells. The former frequently formed tubular and papillary structures. The tumor was not encapsulated, and invasion of adjacent muscle tissue was noted. Although the cytologic differentiation from cellular variants of pleomorphic adenoma and myoepithelioma is difficult, the feature of palisading tumor cells may be useful in the differential diagnosis.
描述了从舌根部多形性低度恶性腺癌（PLGA）细针穿刺获得的细胞学特征。肿瘤细胞由立方上皮细胞和短梭形肌上皮样细胞组成，它们形成大的细胞团。在细胞团的中央部分，有黏液样物质，偶尔可见栅栏状排列的肿瘤细胞围绕着它们。组织学检查显示立方上皮细胞和梭形细胞呈实性增生。前者常形成管状和乳头状结构。肿瘤无包膜，可见侵犯邻近肌肉组织。虽然从多形性腺瘤和肌上皮瘤的细胞变体进行细胞学鉴别很困难，但栅栏状排列的肿瘤细胞特征可能有助于鉴别诊断。
