Morton N E, Sherman S L, MacLean S, Yee S, Lew R
Population Genetics Laboratory, University of Hawaii, Honolulu, HI.
Genet Epidemiol. 1984;1(2):195-9. doi: 10.1002/gepi.1370010214.
A combined segregation, linkage, and association analysis using the program COMBIN was performed on the simulated pedigree data prepared for the Second Genetic Analysis Workshop. The model used in COMBIN is described and the presented results illustrate its effectiveness in the analysis of such data. Linkage analysis was performed and maps for each linkage group are presented.
使用COMBIN程序对为第二次遗传分析研讨会准备的模拟家系数据进行了综合分离、连锁和关联分析。描述了COMBIN中使用的模型,给出的结果说明了该模型在分析此类数据方面的有效性。进行了连锁分析并给出了每个连锁群的图谱。