Demenais F, Darlu P
Unité de Rercherche de Génétique Epidémiologique. INSERM U. 155, Paris, France.
Genet Epidemiol. 1984;1(2):171-4. doi: 10.1002/gepi.1370010209.
Segregation and linkage analyse were performed on Problem 2 simulated data. Segregation analysis showed evidence for nearly recessive major susceptibility locus with parameter estimates close to the simulation input values. Linkage between this susceptibility locus (X) and the ten marker loci (A to J) led us to propose the following map: X-G-F-B.
对问题2模拟数据进行了分离分析和连锁分析。分离分析显示存在一个几乎隐性的主要易感基因座的证据，参数估计值接近模拟输入值。这个易感基因座（X）与十个标记基因座（A至J）之间的连锁关系使我们提出了以下图谱：X-G-F-B。
