Reed May J, Edelberg Jay M
Department of Medicine, Division of Gerontology and Geriatric Medicine, University of Washington, Seattle, WA 98104, USA.
Sci Aging Knowledge Environ. 2004 Feb 18;2004(7):pe7. doi: 10.1126/sageke.2004.7.pe7.
The process of angiogenesis, during which new blood vessels are formed, is impaired during aging. This Perspective describes many of the myriad components of the angiogenic response that are altered with age. In addition, the impact of impaired angiogenesis on wound healing, vascular disease, and cancer in the aged is discussed.