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Abnormal mRNA expression of ASPP members in leukemia cell lines.

作者信息

Liu Z-J, Zhang Y, Zhang X-B, Yang X

出版信息

Leukemia. 2004 Apr;18(4):880. doi: 10.1038/sj.leu.2403300.

DOI:10.1038/sj.leu.2403300
PMID:14973501
Abstract
摘要

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Abnormal mRNA expression of ASPP members in leukemia cell lines.ASPP家族成员在白血病细胞系中的异常mRNA表达。
Leukemia. 2004 Apr;18(4):880. doi: 10.1038/sj.leu.2403300.
2
Downregulated mRNA expression of ASPP and the hypermethylation of the 5'-untranslated region in cancer cell lines retaining wild-type p53.在保留野生型p53的癌细胞系中,ASPP的mRNA表达下调以及5'-非翻译区的高甲基化。
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iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.iASPP癌蛋白是一种从线虫到人类都保守的p53关键抑制剂。
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Abnormal expression pattern of the ASPP family of proteins in human non-small cell lung cancer and regulatory functions on apoptosis through p53 by iASPP.ASPP 家族蛋白在人非小细胞肺癌中的异常表达模式及其通过 iASPP 对凋亡的调控作用与 p53 相关。
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ASPP--Apoptotic specific regulator of p53.ASPP——p53的凋亡特异性调节因子。
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siRNA-mediated down-regulation of iASPP promotes apoptosis induced by etoposide and daunorubicin in leukemia cells expressing wild-type p53.小干扰RNA介导的iASPP下调促进拓扑替康和柔红霉素在表达野生型p53的白血病细胞中诱导的凋亡。
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Susceptibility to cytosine arabinoside (Ara-C)-induced cytotoxicity in human leukemia cell lines.人白血病细胞系对阿糖胞苷(Ara-C)诱导的细胞毒性的敏感性。
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[Apoptosis and regulation of expressions of apoptosis-related gene Bcl-2 and p53 induced by selenium dioxide in three leukemia cell lines].[二氧化硒诱导三种白血病细胞系凋亡及凋亡相关基因Bcl-2和p53表达的调控]
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The family of apoptosis-stimulating proteins of p53 is dysregulated in colorectal cancer patients.p53凋亡刺激蛋白家族在结直肠癌患者中表达失调。
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The lncRNA XIST interacts with miR-140/miR-124/iASPP axis to promote pancreatic carcinoma growth.长链非编码RNA XIST与miR-140/miR-124/iASPP轴相互作用以促进胰腺癌生长。
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In vitro effect of iASPP on cell growth of oral tongue squamous cell carcinoma.iASPP 对口腔舌鳞癌细胞生长的体外影响。
Chin J Cancer Res. 2014 Aug;26(4):382-90. doi: 10.3978/j.issn.1000-9604.2014.07.05.
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MicroRNA124 regulate cell growth of prostate cancer cells by targeting iASPP.微小RNA124通过靶向iASPP调控前列腺癌细胞的细胞生长。
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