Tetsumoto K, Küchle M, Naumann G O
Department of Ophthalmology, University of Erlangen-Nürnberg, Germany.
Arch Ophthalmol. 1992 Aug;110(8):1119-23. doi: 10.1001/archopht.1992.01080200099033.
We studied three sector iridectomy specimens from three patients who had undergone neodymium:YAG (Nd:YAG) laser iridotomies 3 to 5 years earlier for treatment of imminent angle closure glaucoma. The specimens were obtained during cataract extraction and were examined by light and transmission electron microscopy. In all iris specimens, the edges of the iridotomy sites consisted of loosely arranged melanocytes, fibrocytes, and vessels. In the iris stroma, there were numerous pigment-laden cells. The iris vessels appeared to be intact; there were no fibrinous aggregates, no inflammatory response or scarring, nor any signs of proliferation of the iris pigment epithelium. Our findings suggest that in humans, iris wound healing after Nd:YAG laser iridotomy occurs without induction of fibrous scars or proliferation of the iris pigment epithelium. This indicates that there is no tendency toward late closure of the iridotomy sites.
我们研究了三名患者的三例扇形虹膜切除术标本，这些患者在3至5年前接受了钕:钇铝石榴石（Nd:YAG）激光虹膜切开术，用于治疗即将发生的闭角型青光眼。这些标本是在白内障摘除术中获取的，并通过光镜和透射电子显微镜进行检查。在所有虹膜标本中，虹膜切开部位的边缘由排列松散的黑素细胞、纤维细胞和血管组成。在虹膜基质中，有许多充满色素的细胞。虹膜血管似乎完好无损；没有纤维蛋白聚集体，没有炎症反应或瘢痕形成，也没有虹膜色素上皮增殖的迹象。我们的研究结果表明，在人类中，Nd:YAG激光虹膜切开术后虹膜伤口愈合过程中不会诱导纤维瘢痕形成或虹膜色素上皮增殖。这表明虹膜切开部位没有晚期闭合的趋势。
