Schimmel D, Erler W, Putsche R, Jacob B
Institut für bakterielle Tiereuchenforschung Jena-Zwätzen.
Berl Munch Tierarztl Wochenschr. 1992 Jul 1;105(7):233-5.
The i. m. application of dermonecrotoxin of P. multocida var. D led to an atrophy of nasal conchae, liver-swelling and to induration of liver and spleen. The intratracheal application caused a lobular pneumonia. The vaccination with toxoid resulted in an immunity against a challenge with toxin but not with P. multocida var. D. Correlations between antitoxic serum-titers and immunity have to be investigated in future.
多杀性巴氏杆菌D型皮肤坏死毒素肌肉注射会导致鼻甲萎缩、肝脏肿大以及肝脾硬结。气管内注射会引发小叶性肺炎。类毒素疫苗接种可产生针对毒素攻击的免疫力,但对多杀性巴氏杆菌D型无效。抗毒素血清滴度与免疫力之间的相关性有待进一步研究。