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消化性溃疡后壁穿孔:一种罕见外科急症的临床表现与结局

Posterior perforation of peptic ulcers: presentation and outcome of an uncommon surgical emergency.

作者信息

Wong Chin-Ho, Chow Pierce K H, Ong Hock-Soo, Chan Weng-Hoong, Khin Lay-Wai, Soo Khee-Chee

机构信息

Department of General Surgery, Singapore General Hospital, Singapore.

出版信息

Surgery. 2004 Mar;135(3):321-5. doi: 10.1016/j.surg.2003.11.001.

Abstract

BACKGROUND

Posterior perforation of peptic ulcer is a distinct clinical entity not commonly encountered. This report evaluates the presentation, diagnosis, management, and outcome of this acute surgical condition.

METHODS

We reviewed records of 9 patients with posterior perforations who were treated at our institution from January 1990 to June 2002.

RESULTS

This condition was characterized by insidious onset of upper abdominal pain and delayed presentation. Abdominal examinations were equivocal in 7 patients on admission. Pneumoperitoneum on chest roentgenogram, when present, was a crucial diagnostic indicator of intra-abdominal pathology. The diagnosis was made intraoperatively in all cases; findings were sealed perforation, localized retroperitoneal abscess, or generalized contamination of the lesser sac and peritoneal cavity. Observed adverse operative risk factors included prolonged perforation (>24 hours), pre-existing chronic medical illnesses, and preoperative hypotension. In addition, significant peritoneal contamination at celiotomy, major resection (gastrectomy), and gastric perforations were noted to be associated with a poor outcome: 4 of the 9 patients died.

CONCLUSION

A high index of suspicion is important. When a retroperitoneal collection is noted at celiotomy, posterior perforation of peptic ulcer should be actively excluded.

摘要

背景

消化性溃疡后壁穿孔是一种不常见的独特临床病症。本报告评估了这种急性外科疾病的临床表现、诊断、治疗及预后。

方法

我们回顾了1990年1月至2002年6月在我院接受治疗的9例后壁穿孔患者的病历。

结果

该病症以上腹部疼痛隐匿起病和就诊延迟为特征。7例患者入院时腹部检查结果不明确。胸部X线片上出现气腹时,是腹内病变的关键诊断指标。所有病例均在术中确诊;发现为封闭性穿孔、局限性腹膜后脓肿或小网膜囊及腹腔广泛污染。观察到的不良手术风险因素包括穿孔时间延长(>24小时)、既往慢性疾病以及术前低血压。此外,剖腹术时明显的腹膜污染、大手术切除(胃切除术)以及胃穿孔与不良预后相关:9例患者中有4例死亡。

结论

高度怀疑很重要。当剖腹术时发现腹膜后积液时,应积极排除消化性溃疡后壁穿孔。

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