Almeyda Robert, Kothari Prasad, Chau Ha, Cumberworth Vincent
Department of Otolaryngology, West Middlesex Hospital, Isleworth, UK.
J Laryngol Otol. 2004 Feb;118(2):156-8. doi: 10.1258/002221504772784667.
Neurilemmomas are slow growing, benign neoplasms of neural crest Schwann cell origin. They arise from any peripheral, spinal or cranial nerve except the olfactory and optic. Presentation is usually asymptomatic but focal neurological signs and symptoms may be associated with nerve compression. With approximately one third of all documented cases presenting in the head and neck region, we report a case of a submandibular neurilemmoma misdiagnosed pre-operatively. The diagnostic difficulties are discussed and the current literature reviewed. This case highlights the importance of inclusion of nerve sheath tumours in differential diagnoses of soft tissue lesions in the head and neck.
神经鞘瘤是一种生长缓慢的良性肿瘤，起源于神经嵴施万细胞。它们可发生于除嗅神经和视神经外的任何外周神经、脊神经或颅神经。通常表现为无症状，但局灶性神经体征和症状可能与神经受压有关。在所有已记录的病例中，约三分之一发生在头颈部区域，我们报告一例术前误诊的下颌下神经鞘瘤病例。讨论了诊断困难并回顾了当前文献。该病例强调了在头颈部软组织病变的鉴别诊断中纳入神经鞘瘤的重要性。
