Peluso A M, Fanti P A, Monti M, Bardazzi F, Tosti A
Department of Dermatology, University of Bologna, Italy.
Dermatology. 1992;184(2):129-32. doi: 10.1159/000247520.
Five patients who developed severe cutaneous complications after artificial hair implantation were subjected to a scalp biopsy. The pathology showed the presence of hyperplastic epidermal proliferations that produced infundibulum-like structures around the implanted fibers in the superficial dermis. A dense acute inflammatory infiltrate surrounded the artificial fibers in the superficial dermis. In the deep dermis a granulomatous infiltrate was present whereas in the hypodermis the inflammatory infiltrate was sparse and the fibers were embedded in fibroplasia. The pathology of a patient who did not present any skin inflammation after artificial hair implantation showed similar pathological features but the absence of acute inflammation suggesting that bacterial infections play a major role in the development of the cutaneous complications of hair implantation. Since definitive treatment of the infections is ineffective until the fibers are removed from the scalp, surgical treatment was required in 2 of our patients.
五名在人工植发后出现严重皮肤并发症的患者接受了头皮活检。病理显示存在增生性表皮增生，在真皮浅层围绕植入的纤维形成漏斗状结构。真皮浅层有密集的急性炎性浸润围绕着人工纤维。在真皮深层存在肉芽肿性浸润，而在皮下组织炎性浸润稀疏，纤维嵌入纤维增生中。一名在人工植发后未出现任何皮肤炎症的患者的病理显示出类似的病理特征，但无急性炎症，这表明细菌感染在植发皮肤并发症的发生中起主要作用。由于在纤维从头皮移除之前对感染的确定性治疗无效，我们的两名患者需要进行手术治疗。
