来自药用愈创木树皮的三萜皂苷

Triterpenoid saponin from the bark of Guaiacum officinale L.

作者信息

Ahmad Viqar Uddin, Saba Nikhat, Khan Khalid Mohammed

机构信息

H.E.J. Research Institute of Chemistry, International Centre for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan.

出版信息

Nat Prod Res. 2004 Apr;18(2):111-6. doi: 10.1080/1478641031000140866.

DOI:10.1080/1478641031000140866

PMID:14984082

Abstract

A new triterpenoid saponin, guaianin R (1) was isolated from the n-BuOH extract of bark of Guaiacum officinale L. It was characterized as akebonic acid-3-O-[alpha-L-rhamnopyranosyl-(1 --> 3)-beta-D-glucopyranosyl-(1 --> 3)-alpha-L-rhamnopyranosyl-(1 --> 2)-alpha-L-arabinopyranoside]-28-O-[beta-D-glucopyranosyl]-ester. The structure was established with the help of a comparative study of 1D and 2D 1H- 13C NMR methods. A number of other saponins were isolated and reported from the same species.

摘要

从愈创木（Guaiacum officinale L.）树皮的正丁醇提取物中分离出一种新的三萜皂苷，愈创木苷R（1）。其结构被鉴定为秋波酸-3-O-[α-L-鼠李糖基-(1→3)-β-D-葡萄糖基-(1→3)-α-L-鼠李糖基-(1→2)-α-L-阿拉伯糖苷]-28-O-[β-D-葡萄糖苷]-酯。通过一维和二维氢-碳核磁共振方法的比较研究确定了其结构。还从同一物种中分离并报道了许多其他皂苷。