细胞分裂中纺锤体形成的计算机建模。

Computer modeling of pole formation in cell division.

作者信息

Czihak G, Linhart J

机构信息

Institute of Genetics and Developmental Biology, University of Salzburg, Austria.

出版信息

Math Biosci. 1992 Jul;110(2):175-80. doi: 10.1016/0025-5564(92)90035-u.

DOI:10.1016/0025-5564(92)90035-u

PMID:1498447

Abstract

The regular position of spindle poles in bi- and multipolar cell divisions is interpreted as the result of expanding caps on the surface of cell nuclei first proposed by Mazia in 1986. In a computer model it is shown that expanding caps position their centers with the maximal distance between them, which is in complete accordance with findings in experimentally influenced cell divisions in which multiple poles are formed.

摘要

纺锤极在双极和多极细胞分裂中的常规位置被解释为细胞核表面扩展帽的结果，这一观点最早由马齐亚于1986年提出。在一个计算机模型中显示，扩展帽将它们的中心定位在彼此之间的最大距离处，这与在实验诱导形成多个极的细胞分裂中的发现完全一致。