Disdier P, Swiader L, Harlé J R, Pellissier J F, Figarella-Branger D, Veit V, Gérolami A, Arlet P h, Weiller P J
Service de Médecine Interne, Hôpital de la Timone, Marseille, France.
Am J Gastroenterol. 1997 May;92(5):880-2.
We report two cases of gastrocnemius muscle vasculitis revealing Crohn's disease. Gastrocnemius muscle biopsy evidenced a necrotizing vasculitis resembling panarteritis nodosa in one case; a nonnecrotizing vasculitis was found in the other case. Neither of the patients had systemic vasculitic involvement, and the muscle disease resembled calf muscle-located panarteritis nodosa. Our literature review shows five cases of calf-located myalgia occurring during Crohn's disease characterized by heterogenous histopathological findings including vasculitic and myositic lesions. Thus, faced with calf-located myalgia with vasculitis or myositis, a search for Crohn's disease is probably necessary to determine precisely the frequency and the etiopathogenic mechanisms of this association.
我们报告了两例提示克罗恩病的腓肠肌血管炎病例。一例腓肠肌活检显示为坏死性血管炎，类似于结节性多动脉炎；另一例为非坏死性血管炎。两名患者均无系统性血管炎累及，肌肉疾病类似于位于小腿肌肉的结节性多动脉炎。我们的文献综述显示，有五例在克罗恩病期间出现的小腿部肌痛病例，其组织病理学表现各异，包括血管炎和肌炎病变。因此，面对伴有血管炎或肌炎的小腿部肌痛，可能有必要排查克罗恩病，以准确确定这种关联的发生率和病因机制。
