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Overgrowth and pruning of dendrites in adult rats recovering from neocortical damage.

作者信息

Jones T A, Schallert T

机构信息

Department of Psychology, University of Texas, Austin 78712.

出版信息

Brain Res. 1992 May 22;581(1):156-60. doi: 10.1016/0006-8993(92)90356-e.

DOI:10.1016/0006-8993(92)90356-e
PMID:1498666
Abstract

Unilateral lesions to the forelimb representation (FL) area of the rat sensorimotor cortex caused a time-dependent increase in the dendritic arborization of layer V pyramidal neurons in the contralateral homotopic cortex. The increase in arborization was maximum at 2-3 weeks after the lesion, following which there was a partial reduction in dendritic branching. These neural morphological changes may be related to post-lesion behavioral changes in the use of the forelimbs.

摘要

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