Buysse Daniel J
Sleep and Chronobiology Program, Department of Psychiatry, University of Pittsburgh School of Medicine, USA.
Geriatrics. 2004 Feb;59(2):47-51; quiz 52.
Insomnia and depression are related to each other on the level of epidemiology, clinical presentation, neurobiology, and treatment implications. The changes in sleep seen in older adults make these relationships particularly strong. Epidemiological studies show that depression is one of the strongest risk factors for current insomnia, but recent evidence indicates that this relationship is bi-directional: current insomnia is a risk factor for future depression. Changes in objective measures of sleep in depression mirror the changes seen in the aging process. Treating sleep disturbances may improve outcomes in patients with depression. Physicians should routinely question their older patients about sleep problems and depression.
失眠与抑郁在流行病学、临床表现、神经生物学及治疗意义层面相互关联。老年人睡眠方面的变化使这些关系尤为紧密。流行病学研究表明，抑郁是当前失眠最强的风险因素之一，但近期证据显示这种关系是双向的：当前失眠是未来抑郁的一个风险因素。抑郁患者睡眠客观指标的变化反映出衰老过程中出现的变化。治疗睡眠障碍可能改善抑郁患者的预后。医生应常规询问老年患者的睡眠问题及抑郁情况。
