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[准分子激光上皮下角膜磨镶术(LASEK)治疗近视度数达-6.0 D。108只眼术后12个月的结果]

[Laser epithelial keratomileusis (LASEK) for treatment of myopia up to -6.0 D. Results from 108 eyes after 12 months].

作者信息

Gabler B, Winkler von Mohrenfels C, Herrmann W, Lohmann C P

机构信息

Augenklinik der Universität Regensburg, Regensburg.

出版信息

Ophthalmologe. 2004 Feb;101(2):146-52. doi: 10.1007/s00347-003-0885-0.

Abstract

BACKGROUND

Laser epithelial keratomileusis (LASEK) is a new keratorefractive procedure for the correction of myopia and myopic astigmatism, which may combine advantages and eliminate disadvantages of photorefractive keratectomy (e.g. pain, corneal haze) and laser in situ keratomileusis (e.g. flap and interface complications, dry eye, keratectasia). We present the results of 108 consecutively LASEK-treated eyes with a follow-up period of 12 months.

PATIENTS AND METHODS

LASEK was performed on 108 consecutive eyes with myopia or myopic astigmatism using a keracor 117 excimer laser. The mean preoperative refraction was -4.12+/-1.30 diopters (D) spherical equivalent range: -1.75 to -6.0 D and maximal cylinder was 3.25 D. Results of the 12 months visit are available for 101 eyes (93.5%).

RESULTS

No serious complications were observed. After 12 months, SE was within +/-1.0 D of emmetropia in 96% and within +/-0.5 D in 86% of the eyes; 6 eyes had to be retreated. None of the eyes showed haze worse than grade 1 or lost more than one line of best-corrected visual acuity. Uncorrected visual acuity (UCVA) was > or =20/20 in 80% and > or =20/40 in 98%.

CONCLUSIONS

Laser epithelial keratomileusis (LASEK) seems to be safe and effective in treatment of myopia and myopic astigmatism of up to -6.0 D. Preliminary results compare favourably with those after photorefractive keratectomy and laser in situ keratomileusis. Haze formation after LASEK seems to be low. Coverage of the stromal wound with a vital epithelial flap could positively influence postoperative wound healing reactions.

摘要

背景

准分子激光上皮下角膜磨镶术(LASEK)是一种用于矫正近视和近视散光的新型角膜屈光手术,它可能兼具光性屈光性角膜切削术(例如疼痛、角膜混浊)和准分子激光原位角膜磨镶术(例如瓣和界面并发症、干眼、角膜扩张)的优点并消除其缺点。我们报告了连续108只接受LASEK治疗且随访期为12个月的眼睛的结果。

患者和方法

使用Keracor 117准分子激光对连续108只患有近视或近视散光的眼睛进行LASEK手术。术前平均屈光度为-4.12±1.30屈光度(D),等效球镜范围:-1.75至-6.0 D,最大柱镜为3.25 D。101只眼睛(93.5%)有12个月随访结果。

结果

未观察到严重并发症。12个月后,96%的眼睛等效球镜在正视眼±1.0 D范围内,86%的眼睛在±0.5 D范围内;6只眼睛需要再次手术。没有眼睛显示混浊程度超过1级或最佳矫正视力下降超过一行。80%的眼睛未矫正视力(UCVA)≥20/20,98%的眼睛≥20/40。

结论

准分子激光上皮下角膜磨镶术(LASEK)在治疗高达-6.0 D的近视和近视散光方面似乎是安全有效的。初步结果与光性屈光性角膜切削术和准分子激光原位角膜磨镶术后的结果相比更有利。LASEK术后的混浊形成似乎较少。有活力的上皮瓣覆盖基质伤口可能对术后伤口愈合反应产生积极影响。

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