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回顾性研究 30 例大面积和次大面积肺栓塞患者行肺动脉内取栓的短期疗效。

Short-term results of retrograde pulmonary embolectomy in massive and submassive pulmonary embolism: a single-center study of 30 patients.

机构信息

Department of Cardiac Surgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Eur J Cardiothorac Surg. 2011 Oct;40(4):890-3. doi: 10.1016/j.ejcts.2011.06.004. Epub 2011 Jul 8.

Abstract

OBJECTIVE

Surgical pulmonary embolectomy is usually reserved for critically ill patients with pulmonary embolism. The conventional antegrade technique of embolectomy may miss peripheral clots, rendering the patient amenable to developing pulmonary hypertension. Here, we present our experience with a new retrograde pulmonary embolectomy supplementing the current antegrade technique.

METHODS

From January 2004 through December 2010, 30 consecutive patients underwent pulmonary embolectomy in our center. The study included 15 men and 15 women whose age ranged from 28 to 80 years, with mean age of 58±15 years. All the patients except one were taken to the operating room with at least one imaging modality confirming the presence of a large thrombus in pulmonary-arterial vasculature.

RESULTS

The most common presenting symptoms of patients was dyspnea (n=27, 90%). The major indications for surgery were severe hemodynamic or respiratory compromise (n=11, 36%). After performing antegrade embolectomy, retrograde flushing of the pulmonary veins was done. The in-hospital mortality in our study was 6.6% (2/30). Mean intubation time for the patients was 52.7±36.5 h, with a range of 12-120 h. Mean intensive care unit (ICU) admission for the patients was 7 days with a range of 2-60 days.

CONCLUSIONS

As far as we know, this is the largest series of cases published so far regarding the immediate results of retrograde pulmonary embolectomy. This technique can successfully dislodge the remaining clots in distal pulmonary vasculature not directly visualized. Surgical pulmonary embolectomy is a safe method and should not be used as a last resort for patients with pulmonary embolism.

摘要

目的

外科肺动脉血栓切除术通常保留给患有肺栓塞的危重患者。传统的顺行血栓切除术可能会错过周围的血栓,使患者容易发生肺动脉高压。在这里,我们介绍一种新的逆行肺动脉血栓切除术的经验,补充目前的顺行技术。

方法

从 2004 年 1 月到 2010 年 12 月,我们中心连续 30 例患者接受了肺动脉血栓切除术。该研究包括 15 名男性和 15 名女性,年龄 28-80 岁,平均年龄 58±15 岁。除 1 例患者外,所有患者均至少采用一种影像学方法证实肺动脉血管中有大血栓。

结果

患者最常见的表现症状是呼吸困难(n=27,90%)。手术的主要指征是严重的血流动力学或呼吸窘迫(n=11,36%)。在进行顺行血栓切除术之后,进行逆行肺动脉静脉冲洗。我们的研究中住院死亡率为 6.6%(2/30)。患者的平均插管时间为 52.7±36.5 小时,范围为 12-120 小时。患者的平均 ICU 住院时间为 7 天,范围为 2-60 天。

结论

据我们所知,这是迄今为止关于逆行肺动脉血栓切除术的即时结果的最大系列病例。该技术可以成功地清除未直接可视化的远端肺动脉血管中的残留血栓。外科肺动脉血栓切除术是一种安全的方法,不应将其作为肺栓塞患者的最后手段。

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