Huang Z Q
General Hospital of People's Liberation Army, Beijing.
Zhonghua Wai Ke Za Zhi. 1992 Jan;30(1):27-31, 62-3.
A total of 689 operative cases of acute necrotic pancreatitis (ANP) were collected from 42 hospitals all over the country by the ANP Cooperative Study Group in the years of 1987 to 1989. General data, laboratory findings, pathology of the pancreas and the type of surgical treatment were analysed according to the outcome of the patient. The results showed that 37% of the cases were related to cholelithiasis, the highest incidence was in age above 60, and female patients were predominant and with higher mortality. Laboratory findings at admission, WBC greater than 20,000/mm3, Hb greater than 15 g%, blood sugar greater than 200 mg%, serum bilirubin greater than 5 mg%, BUN greater than 20 mg%, and serum calcium less than 7 mg% were related to the markedly elevated mortality rate. Operative findings noted in patients with bloody or cloudy peritoneal fluid, necrotic changes up to 75% of the pancreas, more than 2 areas of extrapancreatic involvements and resection of a large portion of the pancreas was found to be necessary were all related to a higher mortality. And emergency operations performed within 24 hours after the onset of the disease was also related with a highest mortality rate.
1987年至1989年期间，急性坏死性胰腺炎（ANP）协作研究组从全国42家医院收集了689例急性坏死性胰腺炎手术病例。根据患者的治疗结果，分析了一般资料、实验室检查结果、胰腺病理及手术治疗类型。结果显示，37%的病例与胆石症有关，发病率最高的年龄段为60岁以上，女性患者居多且死亡率较高。入院时的实验室检查结果，白细胞大于20000/mm³、血红蛋白大于15g%、血糖大于200mg%、血清胆红素大于5mg%、血尿素氮大于20mg%以及血清钙小于7mg%，均与死亡率显著升高有关。术中发现血性或浑浊的腹腔积液、胰腺坏死面积达75%以上、胰外受累超过2个区域以及发现有必要切除大部分胰腺的患者，其死亡率均较高。发病后24小时内进行的急诊手术死亡率也最高。
