低血糖指数饮食对超重非胰岛素依赖型糖尿病患者的有益作用。
Beneficial effect of low-glycemic index diet in overweight NIDDM subjects.
作者信息
Wolever T M, Jenkins D J, Vuksan V, Jenkins A L, Wong G S, Josse R G
机构信息
Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Ontario, Canada.
出版信息
Diabetes Care. 1992 Apr;15(4):562-4. doi: 10.2337/diacare.15.4.562.
OBJECTIVE
To determine whether low-glycemic index (GI) diets have clinical utility in overweight patients with non-insulin-dependent diabetes mellitus (NIDDM).
RESEARCH DESIGN AND METHODS
Six patients with NIDDM were studied on both high- and low-GI diets of 6-wk duration with metabolic diets with a randomized crossover design. Both diets were of similar composition (57% carbohydrate, 23% fat, and 34 g/day dietary fiber), but the low-GI diet had a GI of 58 compared with 86 for the high-GI diet.
RESULTS
Small and similar amounts of weight were lost on both diets: 2.5 kg on high-GI diet and 1.8 kg on low-GI diet. On the low-GI diet, the mean level of serum fructosamine, as an index of overall blood glucose control, was lower than on the high-GI diet by 8% (P less than 0.05), and total serum cholesterol was lower by 7% (P less than 0.01).
CONCLUSIONS
In overweight patients with NIDDM, reducing diet GI improves overall blood glucose and lipid control.
目的
确定低升糖指数（GI）饮食对非胰岛素依赖型糖尿病（NIDDM）超重患者是否具有临床效用。
研究设计与方法
采用随机交叉设计，对6例NIDDM患者进行为期6周的高GI饮食和低GI饮食的代谢饮食研究。两种饮食的成分相似（碳水化合物57%、脂肪23%，膳食纤维34克/天），但低GI饮食的升糖指数为58，高GI饮食为86。
结果
两种饮食减轻的体重少量且相近：高GI饮食减轻2.5千克，低GI饮食减轻1.8千克。低GI饮食组作为总体血糖控制指标的血清果糖胺平均水平比高GI饮食组低8%（P<0.05），总血清胆固醇低7%（P<0.01）。
结论
在NIDDM超重患者中，降低饮食升糖指数可改善总体血糖和血脂控制。
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