Zhu Ming-Qiang, Wang Li-Qiong, Exarhos Gregory J, Li Alexander D Q
Department of Chemistry and Center for Materials Research, Washington State University, Pullman, Washington 99164, USA.
J Am Chem Soc. 2004 Mar 10;126(9):2656-7. doi: 10.1021/ja038544z.
Thermosensitive gold nanoparticles were fabricated by conjugating Au with a thiol-terminated poly(N-isopropylacrylamide) or PPA; this polymer stabilizer exhibits a temperature transition while undergoing a hydrophilic to hydrophobic transformation. The introduction of PPA onto gold nanoparticles has sensitized Au nanoparticles with unique temperature dependence. At low temperature (25 degrees C), the solutions containing PPA-functionalized gold nanoparticles are transparent, whereas higher temperatures (30 degrees C) lead to opaque suspensions. The thermosensitive property of PPA-functionalized Au nanoparticles is reversible, and the clear-opaque suspensions can be repeated many times.
通过将金与硫醇封端的聚（N-异丙基丙烯酰胺）或PPA共轭制备热敏金纳米颗粒；这种聚合物稳定剂在经历亲水性到疏水性转变时表现出温度转变。将PPA引入金纳米颗粒使金纳米颗粒具有独特的温度依赖性。在低温（25℃）下，含有PPA功能化金纳米颗粒的溶液是透明的，而较高温度（30℃）会导致悬浮液不透明。PPA功能化金纳米颗粒的热敏特性是可逆的，透明-不透明悬浮液可以重复多次。
