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[颞动脉切片免疫荧光直接检查。价值与局限性(作者译)]

[Direct examination in immunofluorescence of temporal artery sections. Value and limitations (author's transl)].

作者信息

Plouvier B, François M, Wattre P, François P, Devulder B

出版信息

Nouv Presse Med. 1978 May 20;7(20):1719-21.

PMID:149956
Abstract

Although invariably seen with immunofluorescence in Giant Cell Temporal Arteritis, deposits of immunoglobulins and complement in the wall of the temporal arteries is nevertheless not specific to his condition. The results of the preliminary study reported here would seem to indicate that this phenomenon is related to the dysimmune state. A simple investigation, temporal artery biopsy with examination in immunofluorescence may be used to provide evidence for a diagnosis of circulating immune complex disease, the type of which can be defined only by the clinicopathological and biological context. Thus the practical value of temporal artery biopsy goes far beyong giant cell arteritis only.

摘要

虽然在巨细胞颞动脉炎中通过免疫荧光总是能看到,但颞动脉壁上免疫球蛋白和补体的沉积并非该疾病所特有的。此处报告的初步研究结果似乎表明,这种现象与免疫失调状态有关。一项简单的检查,即进行颞动脉活检并做免疫荧光检查,可用于为循环免疫复合物疾病的诊断提供证据,而其类型只能通过临床病理和生物学背景来确定。因此,颞动脉活检的实际价值远不止于巨细胞动脉炎。

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[Immunological implications in the pathogenesis of Horton arteritis].
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